Pall Emoke, Alexandra Roman, Groza Ioan
Natural and synthetic biomaterials play an important role in the treatment of different diseases. Current research is trying to obtain different biomaterials with optimized characteristics. Mesenchymal stem cells with biomaterial scaffolds can provide a promising strategy for tissue engineering and cellular delivery. Because these cells are key elements of cell therapy of various diseases, evaluation and use of specific substrates is highly important. Concomitant use of stem cells and biomaterial scaffolds offer a hopeful strategy for tissue engineering. In this review, we examine the applications of the different types of natural scaffolds (collagen, fibrinogen, gelatin etc.) and evaluate their use in combination with stem cells for tissue engineering applications.
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