నైరూప్య

Review On Immunotoxicology: An Emerging Discipline

Ritu Paliwal, Swatantra Singh, Sanjay shukla, Neelam Tandia, Nitesh Kumar and Shailendra Singh

Immunotoxicology is the study of immune dysfunction resulting from exposure of an organism to a xenobiotic. Immunotoxicology is relatively new interdisciplinary scientific field focused on identification and analysis of chemical and, in a broader sense, also physical and biological factors of the environment which can cause unwanted and usually incidental immunomodulations. The immune dysfunction may take the form of immunosuppression, allergy, autoimmunity and inflammatory-based diseases. Immune System plays a critical role in host resistance to disease as well as in normal homeostasis of an organism; identification of immunotoxic risk is significant in the protection of human, animal and wildlife health. In addition, immunotoxicology also investigates the properties of new immunotherapeutic pharmacological products prepared via recombinant DNA techniques (interleukins, interferons, growth factors, anti-inflammation drugs, neuroendocrine hormones, neuropeptides) with regard to their immunotoxic potential and safety of their use