నైరూప్య

Review on Interaction of Serum Albumin with Drug Molecules

Swarup Roy

The interactions of human and bovine serum albumins (HSA and BSA) with various drugs have received great attention now a days due to their significant effect in the biomedical field. Detailed information about the interactions of drugs with serum albumin can be deducted from the data of fluorescence quenching studies, UV-Vis, and circular dichroism spectroscopy. Among the all fluorescence spectroscopy is the most likable one due to its high sensitivity and simplicity. The present review highlights the interaction of various kinds of drugs with HSA and BSA. This review helps in understanding the structural features of drugs crucial for not only their affinity for serum albumin but also their optimum pharmacological activities.